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J. Guy Breitenbucher, Ph.D.

Senior Director of Medicinal Chemistry

Dr. Breitenbucher has 20 year of drug discovery and scientific management experience. Prior to joining DNS as Director of Medicinal Chemistry, Dr. Breitenbucher had roles as head of Combinatorial Chemistry and head of the Pain Discovery Chemistry departments at Johnson & Johnson Pharmaceutical Research and Development. At J&J, Dr. Breitenbucher led drug discovery project teams which advanced multiple compounds into pre-clinical and clinical development in the therapeutic areas of pain, inflammation, and CNS disorders. At J&J Dr. Breitenbucher also participated on in-licensing diligence teams, and managed a number of external scientific collaborations with academia and biotech. Prior to his 11 years at J&J, Dr. Breitenbucher was a senior scientist at Axys Pharmaceuticals in San Francisco, where he worked in the combinatorial chemistry department, and also as a scientist in the medicinal chemistry department at Bristol-Myers-Squibb working in CNS drug discovery. Dr. Breitenbucher received his B.Sc. and M.Sc. in chemistry at California State University at Long Beach and his Ph.D. in organic chemistry at University of California at Riverside. He also pursued postdoctoral studies in natural product synthesis at the University of California Berkeley. Dr. Breitenbucher is co-author/co-inventor on over 80 peer reviewed scientific papers and patent applications and has served on various scientific advisory panels in the area of medicinal chemistry.